Sla: nuova strategia per annullare i danni ai neuroni

Roma, 20 gennaio 2021 – Passo importante verso una futura terapia per la Sla (Sclerosi Laterale Amiotrofica). I ricercatori dell’Università di Edimburgo, finanziati da diverse associazioni di malati, hanno scoperto che il danno prodotto dalla malattia alle cellule nervose potrebbe essere riparato migliorando i livelli di energia fornita dai mitocondri, le centraline energetiche dei neuroni motori, utilizzando farmaci già approvati per altre malattie. Il risultato è descritto sulla rivista Acta Neuropathologica. Gli studiosi, lavorando su modelli di cellule staminali umane ricavate da persone con malattie del motoneurone, hanno scoperto che l’assone, cioè la parte dei neuroni motori che conduce l’impulso elettrico, è più corto rispetto alle cellule sane e il movimento dei mitocondri, che viaggiano su e giù per gli assoni, è indebolito. Ciò è causato dal rifornimento difettoso di energia dei mitocondri, ed è proprio lavorando su questi che si può far tornare l’assone in condizioni normali, secondo gli studiosi. “I nostri dati ci danno la speranza che ripristinando la fonte di energia della cellula (i mitocondri ndr) si possano proteggere gli assoni e le loro connessioni con il muscolo, evitando che siano danneggiati”, spiega Arpan Mehta, coordinatore dello studio. I ricercatori stanno già lavorando per identificare tra quelli esistenti e già approvati, dei farmaci capaci di stimolare i mitocondri e riparare i moto-neuroni. Ciò potrebbe aprire la strada per poterli testare sull’uomo molto più velocemente.

24 thoughts on “Sla: nuova strategia per annullare i danni ai neuroni

  • 336312 705623i would need to make a lot more christmas cards becuase next month is december already- 423128

  • 556751 331551Hi there! I basically want to give a huge thumbs up for the very good data you could have appropriate here on this post. I will likely be coming again to your weblog for far more soon. 6022

  • I’ll right away seize your rss as I can not in finding your e-mail subscription link or e-newsletter service. Do you have any? Please permit me recognise in order that I may just subscribe. Thanks.

  • When I originally commented I clicked the -Notify me when new comments are added- checkbox and now each time a comment is added I get four emails with the same comment. Is there any way you can remove me from that service? Thanks!

  • Thanks for your personal marvelous posting! I quite enjoyed reading it, you are a great author.I will be sure to bookmark your blog and will eventually come back someday. I want to encourage one to continue your great work, have a nice afternoon!

  • It’s a shame you don’t have a donate button! I’d certainly donate to this excellent blog! I guess for now i’ll settle for bookmarking and adding your RSS feed to my Google account. I look forward to brand new updates and will talk about this site with my Facebook group. Talk soon!

  • Nice read, I just passed this onto a colleague who was doing some research on that. And he just bought me lunch as I found it for him smile Therefore let me rephrase that: Thanks for lunch!

  • Hi there! Would you mind if I share your blog with my twitter group? There’s a lot of folks that I think would really enjoy your content. Please let me know. Many thanks

  • Thanks for any other fantastic article. The place else may just anybody get that kind of info in such a perfect method of writing? I have a presentation next week, and I am at the search for such info.

  • I’m still learning from you, but I’m trying to achieve my goals. I certainly enjoy reading all that is written on your website.Keep the tips coming. I liked it!

  • hi!,I love your writing very much! percentage we be in contact more about your article on AOL? I require an expert in this space to resolve my problem. May be that is you! Looking ahead to see you.

  • I’m impressed, I must say. Really not often do I encounter a blog that’s each educative and entertaining, and let me let you know, you have hit the nail on the head. Your thought is excellent; the issue is something that not sufficient persons are speaking intelligently about. I am very pleased that I stumbled throughout this in my seek for something referring to this.

  • Precisely what I was looking for, regards for putting up.

  • Great post. I am facing a couple of these problems.

  • excellent issues altogether, you simply gained a logo new reader. What would you recommend about your put up that you just made a few days ago? Any sure?

  • Nice blog here! Also your web site loads up very fast! What host are you using? Can I get your affiliate link to your host? I wish my site loaded up as fast as yours lol

  • Pretty portion of content. I just stumbled upon your web site and in accession capital to say that I acquire in fact loved account your weblog posts. Any way I’ll be subscribing in your feeds and even I fulfillment you access persistently rapidly.

  • Hi there, You’ve performed an excellent job. I’ll certainly digg it and individually recommend to my friends. I’m confident they’ll be benefited from this site.

  • Do you mind if I quote a couple of your posts as long as I provide credit and sources back to your weblog? My website is in the exact same niche as yours and my users would really benefit from a lot of the information you present here. Please let me know if this alright with you. Thanks a lot!

  • Oh my goodness! an incredible article dude. Thank you Nevertheless I’m experiencing problem with ur rss . Don’t know why Unable to subscribe to it. Is there anyone getting equivalent rss problem? Anybody who is aware of kindly respond. Thnkx

Lascia un commento

Il tuo indirizzo email non sarà pubblicato. I campi obbligatori sono contrassegnati *